Integrated multi-omics analysis and microbial recombinant protein system reveal hydroxylation and glycosylation involving nevadensin biosynthesis in Lysionotus pauciflorus

发布时间：2022年09月20日

Integrated multi-omics analysis and microbial recombinant protein system reveal hydroxylation and glycosylation involving nevadensin biosynthesis in Lysionotus pauciflorus

Tianze Wu;Li Xiang, Ranran Gao;Lan Wu;Gang Deng;Wenting Wang;Yongping Zhang;Bo Wang;Liang Shen;Shilin Chen;Xia Liu;Qinggang Yin

2022年9月19日，中国中医科学院中药研究所青蒿素中心以“Integrated multi-omics analysis and microbial recombinant protein system reveal hydroxylation and glycosylation involving nevadensin biosynthesis in Lysionotus pauciforus”为题的研究论文在期刊“Microbial Cell Factories”上在线发表，该研究阐明了吊石苣苔石吊兰素生物合成的羟基化和糖基化机理。贝纳基因承担了该研究中PacBio 3+2全长转录组和广泛靶向代谢组的检测和分析工作。